Many people check for proteinuria during the physical examination. They have protein + number and are positive for protein. When they encounter this situation, they will be afraid of worry. Is it kidney disease? Is proteinuria necessarily a kidney disease? What other circumstances?
Is there a kidney disease in the physical examination protein? Don't be afraid!
Clinically defined proteinuria generally refers to the content of protein in normal urine exceeding 150 mg/day. The protein leaking through the kidneys with urine comes from plasma, and its main component is albumin. Protein leaks from the kidneys, mainly because of the glomerular filtration barrier function of the kidney, or abnormal renal tubular reabsorption.
Generally speaking, there are only a small amount of protein in the urine of healthy people, but if various factors cause disorder of the body's regulation mechanism, and then encounter colds, infections and other factors, it will also lead to immune allergic reactions, anti-inflammatory antibodies. Combined to produce immune complexes, leading to local ischemia and hypoxia of the kidney, damage to endothelial cells, inflammatory cell infiltration, inflammatory response, initiation of renal fibrosis, glomerular pathological changes, glomerular filtration The membrane damage, so the macromolecular protein and red blood cells that are not likely to leak out of the glomerulus, and the renal tubular reabsorption function, so proteinuria appears in clinical tests. |
So proteinuria occurs during the physical examination, don't panic, figure out what caused it! Whether it is physiological or pathological.
1. Physiological proteinuria. If it is affected by strenuous exercise, body position change, body fever or cold, emotional agitation, etc., it is mostly physiological proteinuria. In this case, there are no abnormalities after repeated visits, so there is no need to do any special treatment.
2. Pathological proteinuria. If the urine test shows that the proteinuria is positive, it is very likely that the patient has pathological damage to the kidney, kidney disease has occurred, and further examination is needed to standardize the treatment.
When checking for proteinuria, be sure to focus on this issue and treat it objectively:
1, can not be diagnosed with a single inspection, the first time you check out proteinuria, you need to do a review, while doing further urine sedimentation, red blood cells, white blood cell counts, etc., comprehensive systemic symptoms and test results to diagnose whether there is a kidney Disease or other disease.
2. If it is clear that patients diagnosed with kidney disease due to the presence of positive abnormalities such as proteinuria, it is necessary to carry out normative renal disease treatment actively and early, so as not to delay the optimal timing of renal disease treatment, thereby increasing the difficulty of treatment. So as to cause a multifaceted burden.
It is recommended that healthy people have an annual urine test, especially those with high risk of chronic kidney disease with diabetes, hypertension, family history of kidney disease, rheumatism or a history of long-term use of drugs.